I would begin by removing the plastic bits and soaking them for several hours in a sink with water and fairly strong solution of Mr. Clean and then after they've soaked a long time go after them with a fine bristled tooth brush. If that doesn't work you can go to stronger measures but in the long run, those kinds of plastic parts are relatively inexpensive to replace.

 

Before strong cleaners I would try water and dish soap. It's surprising how well simple water and soap works.

Bon Ammi is a great cleaner for plastics as well. I get the spray foam cans.

 

I'd start wit a dry cloth then a damp one--then mild cleaners if needed.
Never had any plastic parts get real grimy.

 

Powerful dish soap first
Goo Buster if need

 

Same here, lukewarm water with a bit of dish soap and a toothbrush for creases, like on knobs.

 

Myself, because I already own it, I've used Mother's pre wax cleaner (car care product). Does a great job. I use it on the paint as well. Granted, I've never had a guitar so filthy I have the need for anything stronger.

 

I hit plastics with Gibson spray polish, works fine. If it’s that bad though I would take off the plastics to clean underneath.

 

Sink full with warm water, dish soap, and old toothbrush. They'll look perfect.

 

I use an old brush on an electric toothbrush with regular dish soap and water

 

Kind of overkill but I use a bit of dish soap and vinegar in my ultrasonic jewellery cleaner

 

Dish soap and water, with your regular dish brush or toothbrush to scrub. If it needs more than that, knobs are relatively inexpensive and plentiful.

Dawn is the bomb.

 

Good thing I own a few toothbrushes, eh?
Now this means I'm going to have to take the whole dang 'guard off, remove the pickups... uhh, it's like I wasn't looking for a project, yet I love doing this kinda stuff. It'll be interesting in an investigative sort of way, I guess.

 

I've had good luck using warm soapy water with a soft toothbrush for plastic parts. For tougher grime, a bit of baking soda on a damp cloth works well. If you're using an ultrasonic cleaner, keep the temperature low to avoid damage. Speaking of ultrasonic tech, I recently came across https://www.kaijo-shibuya.com/ultrasonic-liquid-flow-meter/, which is more for industrial use but still interesting to see how ultrasonic systems work.

 

I’ve had good results using a mild dish soap with warm water and a soft toothbrush. For stubborn grime, a bit of baking soda on a damp cloth works well too.

Same for me,

 

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