It basically boils down to how strong your fingers are. The more you play the stronger they get and there is the physical thing about hand size. Whatever guage you can twist and it feels right then that is what to use. Also depends on how much bending you do and how far you like to go with them. The 335 is much like a les paul except it's got a pair of gull wings, try what you use on your paul and see how it feels..... :wave: