For little screws with no real load (pickguards) a pencil shaving works. Get a big solid curl going from a pencil, or a wooden dowel, trim it and glue that in pointy end first. Let the glue set a bit then put the screw back The screw self centers when put in. its practically invisible after it’s dried up. Old antique trick.
For neck screws, put a dowel plug in! Those screws are holding a few hundred pounds of load when tightened right.
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